The present study aims to design and validate a model of cultural development pathologies in Central Asia. In order to process the problem, a qualitative research strategy and thematic analysis were used.The research data were collected using semi-standard interviews with18experts in the field of regional studies(Central Asia) who were selected usin the theoretical sampling method, and a network of analyzed themes and a network measurement conceptual model were constructed usingthe thematic analysis method. The article raises the question of what are the most important pathologies or challenges that contribute to the failure of realization of cultural development in Central Asia ?In response to the findings of the qualitative research, the model of cultural development pathologies in Central Asia includes four overarching themes: 1lack of civil society and independent media, including the theme (weak media and censorship; issues and administrative problems related to the government and the weakness of culture building in relation to civil society); 2The weakness of democratic culture, consisting of two themes(supporter follower culture and weakness of public culture); 3The low level of education indicators, consisting of two themes(structural and managerial weaknesses in educational institutions and parallel work and legal and executive multi functionality);and 4Regional and trans regional challenges, consistingof two themes(competition of regional and trans regional powers and the effects of globalization on regional culture).